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Amro O, Alarab A, AL-Talahma M. Neurodynamic and Wrist Glide Exercises: Effects on Function and Symptom Severity in Carpal Tunnel Syndrome. PTJ 2026; 16 (S1) :457-466
URL: http://ptj.uswr.ac.ir/article-1-730-en.html

Purpose: This study aimed to assess the effects of neurodynamic wrist exercises and wrist glide exercises on symptom severity, range of motion (ROM), grip strength, and hand function in adults with mild to moderate carpal tunnel syndrome (CTS).
Methods: A quasi-experimental study with a pre-post intervention design was conducted in a sample of 30 adult patients with mild to moderate CTS occurring in 50 hands that fulfilled the inclusion criteria. The participants were divided into two intervention groups, and one group received neurodynamic nerve gliding exercises, and the other group received wrist glide exercises. It took place over four weeks. The visual analog scale (VAS) to measure the intensity of pain, Boston carpal tunnel questionnaire (BCTQ), symptom severity scale (SSS), and functional status scale (FSS) to assess pain and functional and symptomatic outcomes, grip strength, and wrist ROM were used to assess pain and functional and symptomatic outcomes before and after the intervention. With this design, within-group and between-group comparisons were used to determine the effectiveness of both interventions. 
Results: The results indicated a significant decrease in pain levels, with average visual analog scale (VAS) scores dropping from 7.20 to 2.64 after the intervention. The average grip strength increased significantly, rising from 227.2 Newtons to a level exceeding 310 Newtons. The SSS and FSS scores showed significant enhancement, with the SSS decreasing from 3.11 to 1.98 and the FSS decreasing from 3.1 to 1.96. The ROM for wrist movements also demonstrated significant improvements. Flexion increased from 71.24 to 76.84 degrees, while extension increased from 72.68 to 77.62 degrees. Significant improvements were observed in ulnar and radial deviations, as well as thumb flexion and abduction.
Conclusion: Neurodynamic wrist and gliding exercises markedly alleviated symptoms in individuals with mild to moderate CTS, diminishing pain, augmenting grip strength, and enhancing ROM, particularly in the thumb.