Fasihi L, Shahrbanian S, Jahangiri M. Effects of Combined Training on Fatigue in People with Multiple Sclerosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. PTJ 2025; 15 (1)
URL:
http://ptj.uswr.ac.ir/article-1-665-en.html
1- Department of Sport Science, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran.
Abstract: (1131 Views)
Purpose: One of the biggest factors reportedly interfering with the lives of those suffering with multiple sclerosis (MS) is fatigue. Prior research has demonstrated that combination training may benefit patients with MS. It hasn't been studied, nevertheless, how combined exercise can lessen fatigue in people with MS. The aim of this systematic review and meta-analysis was to summarize the results of studies that examine the effects of combined training on fatigue in individuals with MS.
Methods: We investigated randomised controlled studies (RCTs) that examined how combination training affected fatigue and were published during the start of the research until May 2024. The Wiley online library, PubMed, MEDLINE, Pedro, Science Direct, and Frontiers were among the electronic databases that were searched. PEDro and McMaster’s measures were used to assess the quality of included research.
Results: The study's requirements were satisfied by six RCTs with 279 participants. Using a random effect model of meta-analysis, the weighted mean differences of fatigue were 1.81 (2.83-0.79), p = 0.002. It appears that exercise training is useful in lowering fatigue in individuals with MS since all included randomized controlled trials (RCTs) revealed significant differences between the subjects assigned to the combined exercise group and the control group.
Conclusions: According to the results, combining exercise can be a useful strategy for helping individuals with MS manage their weariness.
Type of Study:
Research |
Subject:
General Received: 2024/08/5 | Accepted: 2024/09/10 | Published: 2024/01/13