en عمومى General مرور سیستماتیک/ آنالیز متا Systematic Review <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Tahoma;"><span style="line-height:2;"><b>Objective:</b> This structured review seeks to examine the effects of fatigue on lower-limb biomechanics in individuals exhibiting Dynamic Knee Valgus (DKV).<br> <b>Methods:</b> <span lang="EN-GB">We conducted a comprehensive review using Scopus, Web of Science, and PubMed, spanning from the launch of these databases until January 5, 2025. To measure the effect of fatigue, we employed Hedges&#39; g as the effect size, calculating 95% confidence intervals (CIs) through either random-effects or fixed-effects models. A random-effects model was used when I&sup2; values exceeded 50%. Both reviewers evaluated the risk of bias by applying the Newcastle-Ottawa Scale (NOS) for quality assessment. </span><span style="font-family:"Times New Roman",serif"></span><br> <b>Results:</b> Following the screening phase, six studies involving an aggregate of 171 subjects were incorporated into the review. Findings from the meta-analysis revealed that the fatigue intervention resulted in an amplified knee valgus angle in the dominant limb (effect size; -0.78, 95% CI= -1.56_-0.01, P&thinsp;=&thinsp;0.001), alongside a notable increase in the knee valgus angle of the non-dominant limb (effect size; -0.56, 95% CI= -0.78_-0.21, P&thinsp;=&thinsp;0.001).<br> <b>Conclusion:</b> The results indicated that fatigue-inducing protocols substantially heightened the DKV angle in both the dominant and non-dominant lower limbs of the subjects. The increase in knee valgus angles due to fatigue highlights a critical area for intervention and monitoring. By addressing these changes, professionals can enhance injury prevention strategies, optimize athletic performance, and improve rehabilitation outcomes for individuals with DKV. Nonetheless, the results of this study must be viewed with caution because of the diversity in fatigue protocols, differences in biomechanical assessment methods, and the challenges posed by small sample sizes.</span></span></span></div> Knee Valgus, Biomechanics, Fatigue, Kinetics, Kinematics 0 0 http://ptj.uswr.ac.ir/browse.php?a_code=A-10-700-2&slc_lang=en&sid=1 Leila Hamzeh leilahamzeh61@gmail.com Yes Department of Sports Biomechanics, Faculty of Sport Science and Physical Education, Central Tehran Branch, Islamic azad Umiversity, Tehran, Iran. Amirali Jafarnejadgero amiralijafarnezhad@gmail.com No Department of Sport Biomechanics, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran. Hashem Piri hpiri1984@gmail.com No Department of Corrective Exercise and Sport Injury, Faculty of Physical Education and Sport Sciences, Allameh Tabataba’i University, Tehran, Iran. Farhad Tabatabai Ghomsheh Tabatabai.uswr@gmail.com No Ergonomy Group, Tehran University of Medical Sciences, Tehran, Iran.